CSF stands for cerebrospinal fluid. It is a transparent, non-colored fluid that is found in the spinal cord and brain. The spinal cord and the brain form your central nervous system. The central nervous system regulates and coordinates your actions including muscle movements organ function, as well as even the most complex thinking and planning.
IgG is an abbreviation for immunoglobulin G IgG is a form of the antibody. Antibodies are the proteins created by your immune system to combat bacteria, viruses, as well as other harmful substances. A CSF IgG index is a measure of the amount of IgG in the cerebrospinal fluid. You can know more about CSF antibodies via www.bosterbio.com/anti-gm-csf-picoband-trade-antibody-pb9003-boster.html.
Granulocyte-Macrophage Colony-Stimulating Virus (GM-CSF) is a growth factor created by many lymphoid cell types. It interacts with receptor heterodimers composed of an alpha chain specific to GM-CSF and a common beta chain used by receptors with a high affinity that are responsible for IL-3 as well as IL-5.
GM-CSF is a 14.6kDa hematopoietic growth factor that exists in glycosylated and non-glycosylated biologically active forms and stimulates the development of granulocytes, macrophages, early megakaryocytes, and eosinophil progenitor cells. The active version of the GM-CSF protein can be located in extracellular form as a homodimer.
The gene GM-CSF has been found to be located within the cluster of genes located in the chromosome 5q31 region that is thought to be linked with interstitial deletions within the 5q-syndrome, as well as acute myelogenous lymphoma. The cluster also contains other genes that include those that encode interleukins 4, 5, and 13.